Summary
TheDr. Stonemanga series has long come to an end, but with the fourth season of the anime premiering, it’s still fresh in the minds of fans. For anime-only watchers, the best villains in the manga is a topic they’re not well versed in, but manga readers know the various specialties of the multiple villains and how some are definitely more memorable than others.
These villainsgave Senku a run for his moneyas some challenged him with brains and brawn, and an elite few with both.Dr. Stone’svillains are undoubtedly not created equal, and some fans would like to see just how unequal in their villainy they truly are.

8Magma
The Stone World’s Hotheaded Antagonist
This villain was one who might not have had the brains but definitely had the brawn. Magma was one of Ishigami’s strongest and sought to become the Village Chief even if it meant killing off or oppressing his competition. Magma wasn’t big on thinking and tried to use brawn and instincts to solve everything.
His one-track mind made him easy to manipulate, and he fit the very description of ancient civilization warriors before modernization. After the appearance of the pre-petrification humans, Magma grew insecure, hoping to establish his strength and presence by proving he was stronger or simply getting rid of all and any possible obstacles to his dream of becoming chief of Ishigami village.
7Mozu
A Master Of Manipulation And Combat
ThisDr. Stonecharacter wasn’t a primary villain but the secondary antagonist of Treasure Island, but even then, he was enough to put a wedge in the plans of the Kingdom of Science. Despite being a post-petrification human, which is more or less Ancient Civilization, Mozu was battle-intelligent,understood the intricacies of war, and used it to his advantage.
He was described as “selfish, strong as an ox, and calculating to boot.” A description that accurately showed how fearsome he was as an enemy. Mozu was loyal to Ibara and served as his henchman, at least until the Kingdom of Science entered the picture and his life was on the line.
6Hyoga
The Visionary With Both Brains and Brawns
This villain was both highly feared and respected for his physical and intellectual prowess. Hyoga was strong enough to go toe-to-toe with Tsukasa, the strongest primate high schooler at the time. Moreover, he always planned to usurp Tsukasa despite working alongside him and did just that.
As a villain, Hyoga was not above using people’s weaknesses to get to them; even when said weakness was one’s younger sister, as seen with Tsukasa. As every modern scientist knows, Hyoga wasa strong supporter of Social Darwinism. He believed and wholeheartedly supported Darwin’s theory of survival of the fittest, believing the weak to be nothing more than disposable fodder.
5Ibara
A Tyrant Fueled By Greed And Self-Preservation
OfDr. Stone’svarious villains, Ibara’s unique disposition makes him a memorable one. Unlike villains like Tsukasa and Why Man, Ibara was a true villain. He didn’t see himself as “helping the world or giving them a gift,” he simply usurped power from the head of the Kingdom of Petrification on Treasure Island and established himself as a dictatorship, enjoying women, power, and riches as he deemed fit.
As a villain, Ibara had nothing to give the world and simply wanted to take, take, and take some more. He was greedy, manipulative, and extremely scheming, seeing himself as worth more than others. Regardless of whether or not a follower was loyal to him, Ibara would simply use them as a means to an end—an undeniably fitting trait for a villain.
4Stanley Snyder
A Fierce Ally To Dr. Xeno’s Ambitions
This former military soldier served as an antagonist in two arcs. One was the South America Arc, where he was a primary antagonist, and the other was the New America City Arc, where he was a secondary antagonist. As an ex-military soldier, Stanley is a capable combatant and is knowledgeable about the ways of war and military code in general.
His instincts are sharp, and he’s very observant, as expected of a bonafide military man. During the series, Stanley served as a close aide and friend to Dr. Xeno, as he highly supported Xeno’s goal of world dominance. In a sense, he wasto Xeno what Zoro is to Luffy,but on a different side.
3Xeno Houston Wingfield
A Brilliant Mind’s Quest For Control
Like Senku, Dr. Xeno was truly a scientist. Before the petrification, he had worked with NASA and was highly renowned in the field, with even Senku looking up to him. Like Senku, Dr. Xeno was awake throughout his petrification period shouting his ability to act fast and intelligently.
As an individual highly similar to Senku, Dr. Xeno’s twist comes with him seeking world domination after the petrification. He wanted total control of the Stone World and was willing to sacrifice even Senku, a protege he was fond of, to that effect. Xeno wasa villain who had the brainsto challenge Senku, and with individuals like Stanley, he also possessed military power, making him well-equipped overall.
2Tsukasa
The Protector Who Takes Justice Into His Own Hands
Despite being an early villain inDr. Stone, Tsukasa’s role in the overall plot remained ever more significant, and heestablished himself as one of the bestvillains, even better than many of his predecessors in terms of villainy. Tsukasa wasn’t a villain for riches, power, or greed, but because he saw it as an opportunity to cleanse humanity.
This obsession with doing so in a world where cleansing humanity simply meant not reviving them was a borderline delusional act that he wholeheartedly believed, and that greatly fueled his ambitions. Moreover, as the strongest primate high schooler, he had the capability to turn his dreams into reality.
1Why Man
The Entity Behind Humanity’s Fall
The final boss of theDr. Stonemanga series and source of the whole petrification turned out to not be a man at all, but an alien machine/life form imbued with AI. Why Man, the main and overarching antagonist of the series, turned out to be a cluster of the petrification devices themselves,and this discovery was mind-boggling, to say the least.
As an antagonist, Why Man saw itself as superior to humans and gifted them the gift of “eternal life”; however, living eternally while being petrified can hardly be considered as living, and the Kingdom of Science fought back. As a villain, Why Man might not have been the most crafty, but it was undoubtedly what pushed the Kingdom of Science to outdo themselves by going to space to fight off aliens.